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Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine

To determine all potential N-glycosylation sites of a glycoprotein, one central aspect of every bottom-up N-glycoproteomic strategy is to generate suitable N-glycopeptides that can be detected and analyzed by mass spectrometry. Specific proteases, such as trypsin, bear the potential of generating N-...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Pralow, Alexander, Hoffmann, Marcus, Nguyen-Khuong, Terry, Rapp, Erdmann, Reichl, Udo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595805/
https://ncbi.nlm.nih.gov/pubmed/28900186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11668-1
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