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Epigenetic regulation by G9a/GLP complex ameliorates amyloid‐beta 1‐42 induced deficits in long‐term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons

Altered epigenetic mechanisms are implicated in the cognitive decline associated with neurodegenerative diseases such as in Alzheimer's disease (AD). AD is the most prevalent form of dementia worldwide; amyloid plaques and neurofibrillary tangles are the histopathological hallmarks of AD. We ha...

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Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Sharma, Mahima, Dierkes, Tobias, Sajikumar, Sreedharan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595698/
https://ncbi.nlm.nih.gov/pubmed/28665013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12634
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