HIV and drug abuse mediate astrocyte senescence in a β‐catenin‐dependent manner leading to neuronal toxicity

Emerging evidence suggests that cell senescence plays an important role in aging‐associated diseases including neurodegenerative diseases. HIV leads to a spectrum of neurologic diseases collectively termed HIV‐associated neurocognitive disorders (HAND). Drug abuse, particularly methamphetamine (meth...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Yu, Chunjiang, Narasipura, Srinivas D., Richards, Maureen H., Hu, Xiu‐Ti, Yamamoto, Bryan, Al‐Harthi, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595688/
https://ncbi.nlm.nih.gov/pubmed/28612507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12593
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