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Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18–88 years to investigate changes in expression of six genes representing different stages of neurogene...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Mathews, Kathryn J., Allen, Katherine M., Boerrigter, Danny, Ball, Helen, Shannon Weickert, Cynthia, Double, Kay L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595679/
https://ncbi.nlm.nih.gov/pubmed/28766905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12641
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