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Autophagy promotes degradation of polyethyleneimine–alginate nanoparticles in endothelial progenitor cells

Polyethyleneimine (PEI)–alginate (Alg) nanoparticle (NP) is a safe and effective vector for delivery of siRNA or DNA. Recent studies suggest that autophagy is related to cytotoxicity of PEI NPs. However, contribution of autophagy to degradation of PEI–Alg NPs remains unknown. CD34(+)VEGFR-3(+) endot...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wang, Guo-dong, Tan, Yu-zhen, Wang, Hai-jie, Zhou, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595362/
https://ncbi.nlm.nih.gov/pubmed/28924349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S141592
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