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Autophagy promotes degradation of polyethyleneimine–alginate nanoparticles in endothelial progenitor cells

Polyethyleneimine (PEI)–alginate (Alg) nanoparticle (NP) is a safe and effective vector for delivery of siRNA or DNA. Recent studies suggest that autophagy is related to cytotoxicity of PEI NPs. However, contribution of autophagy to degradation of PEI–Alg NPs remains unknown. CD34(+)VEGFR-3(+) endot...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Wang, Guo-dong, Tan, Yu-zhen, Wang, Hai-jie, Zhou, Pei
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595362/
https://ncbi.nlm.nih.gov/pubmed/28924349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S141592
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