Effectiveness and cost-effectiveness of duloxetine added to usual care for patients with chronic pain due to hip or knee osteoarthritis: protocol of a pragmatic open-label cluster randomised trial (the DUO trial)

INTRODUCTION: Osteoarthritis (OA) is a highly prevalent painful condition of the musculoskeletal system. The effectiveness of current analgesic options has proven to be limited and improved analgesic treatment is needed. Several randomised placebo-controlled trials have now demonstrated the efficacy...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: van den Driest, Jacoline J, Schiphof, Dieuwke, Luijsterburg, Pim A J, Koffeman, Aafke R, Koopmanschap, Marc A, Bindels, Patrick J E, Bierma-Zeinstra, Sita M A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
General practice / Family practice
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595178/
https://ncbi.nlm.nih.gov/pubmed/28893757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-018661
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