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Combination of AAV-TRAIL with miR-221-Zip Therapeutic Strategy Overcomes the Resistance to TRAIL Induced Apoptosis in Liver Cancer

TNF-related apoptosis-inducing ligand (TRAIL) possesses the capacity to induce apoptosis in a wide variety of tumor cells without affecting most normal cells. However, it has now emerged that many primary cancer cells are resistant to TRAIL monotherapy. Overcoming the intrinsic or acquired TRAIL res...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Ma, Sisi, Sun, Jiazeng, Guo, Yabin, Zhang, Peng, Liu, Yanxin, Zheng, Dexian, Shi, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595128/
https://ncbi.nlm.nih.gov/pubmed/28900506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19893
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