Uterine cancer after risk-reducing salpingo-oophorectomy without hysterectomy in women with BRCA mutations

IMPORTANCE: The link between BRCA mutations and uterine cancer is unclear. Therefore, although risk-reducing salpingo-oophorectomy (RRSO) is standard treatment among women with BRCA mutations (BRCA+ women), the role of concomitant hysterectomy is controversial. OBJECTIVE: To determine the risk for u...

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Published in:JAMA Oncol
Main Authors: Shu, Catherine A., Pike, Malcolm C., Jotwani, Anjali R., Friebel, Tara M., Soslow, Robert A., Levine, Douglas A., Nathanson, Katherine L., Konner, Jason A., Arnold, Angela G., Bogomolniy, Faina, Dao, Fanny, Olvera, Narciso, Bancroft, Elizabeth K., Goldfrank, Deborah J., Stadler, Zsofia K., Robson, Mark E., Brown, Carol L., Leitao, Mario M., Abu-Rustum, Nadeem R., Aghajanian, Carol A., Blum, Joanne L., Neuhausen, Susan L., Garber, Judy E., Daly, Mary B., Isaacs, Claudine, Eeles, Rosalind A., Ganz, Patricia A., Barakat, Richard R., Offit, Kenneth, Domchek, Susan M., Rebbeck, Timothy R., Kauff, Noah D.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594920/
https://ncbi.nlm.nih.gov/pubmed/27367496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.1820
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