Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption

Alpha-naphthyl isothiocyanate (ANIT) is a common hepatotoxicant experimentally used to reproduce the pathologies of drug-induced liver injury in humans, but the mechanism of its toxicity remains unclear. To determine the metabolic alterations following ANIT exposure, metabolomic analyses was perform...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Toxicology
Autors principals: Wang, Haina, Fang, Zhong-Ze, Meng, Ran, Cao, Yun-Feng, Tanaka, Naoki, Krausz, Kristopher W., Gonzalez, Frank J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594256/
https://ncbi.nlm.nih.gov/pubmed/28549656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2017.05.012
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars