The detectability of the pretreatment EGFR T790M mutations in lung adenocarcinoma using CAST-PCR and digital PCR

BACKGROUND: A gatekeeper T790M mutation is thought to cause resistance to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment. The detection of a 2nd mutation is important for planning the next therapy when patients acquire resistance to the first line EGFR-TKI. METHODS:...

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Dettagli Bibliografici
Pubblicato in:J Thorac Dis
Autori principali: Tatematsu, Tsutomu, Okuda, Katsuhiro, Suzuki, Ayumi, Oda, Risa, Sakane, Tadashi, Kawano, Osamu, Haneda, Hiroshi, Moriyama, Satoru, Sasaki, Hidefumi, Nakanishi, Ryoichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: AME Publishing Company 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594155/
https://ncbi.nlm.nih.gov/pubmed/28932544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2017.07.02
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