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Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors

Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized class of enzymes known as recombinases facili...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Kelso, Andrew A., Waldvogel, Sarah M., Luthman, Adam J., Sehorn, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594099/
https://ncbi.nlm.nih.gov/pubmed/28936205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01716
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