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Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80α dUTPase

The trimeric staphylococcal phage-encoded dUTPases (Duts) are signalling molecules that induce the cycle of some Staphylococcal pathogenicity islands (SaPIs) by binding to the SaPI-encoded Stl repressor. To perform this regulatory role, these Duts require an extra motif VI, as well as the Dut conser...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alite, Christian, Humphrey, Suzanne, Donderis, Jordi, Maiques, Elisa, Ciges-Tomas, J. Rafael, Penadés, José R., Marina, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593958/
https://ncbi.nlm.nih.gov/pubmed/28894239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11234-9
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