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p190RhoGAP proteins contain pseudoGTPase domains

The two p190RhoGAP proteins, p190RhoGAP-A and -B, are key regulators of Rho GTPase signaling and are essential for actin cytoskeletal structure and contractility. Here we report the discovery of two evolutionarily conserved GTPase-like domains located in the ‘middle domain’, previously thought to be...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Stiegler, Amy L., Boggon, Titus J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593906/
https://ncbi.nlm.nih.gov/pubmed/28894085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00483-x
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