Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population

Identification of the primary allele(s) in HLA class II associated diseases remains challenging because of a tight linkage between alleles of HLA-DR and -DQ loci. In the present study, we determined the genotypes of seven HLA loci (HLA-A, -B, -DRB1, -DQA1, -DQB1, -DPA1 and -DPB1) for 1200 Japanese p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yasunami, Michio, Nakamura, Hitomi, Tokunaga, Katsushi, Kawashima, Minae, Nishida, Nao, Hitomi, Yuki, Nakamura, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593890/
https://ncbi.nlm.nih.gov/pubmed/28894202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11148-6
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