Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages

Patients with primary solid malignancies frequently exhibit signs of systemic inflammation. Notably, elevated levels of neutrophils and their associated soluble mediators are regularly observed in cancer patients, and correlate with reduced survival and increased metastasis formation. Recently, we d...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Kersten, Kelly, Coffelt, Seth B., Hoogstraat, Marlous, Verstegen, Niels J.M., Vrijland, Kim, Ciampricotti, Metamia, Doornebal, Chris W., Hau, Cheei-Sing, Wellenstein, Max D., Salvagno, Camilla, Doshi, Parul, Lips, Esther H., Wessels, Lodewyk F.A., de Visser, Karin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593698/
https://ncbi.nlm.nih.gov/pubmed/28919995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1334744
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