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Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a KRAS-driven cancer with a high incidence of metastasis and an overall poor prognosis. Previous work in a genetically engineered mouse model of PDAC showed glucose metabolism to be important for maintaining tumor growth. Multiple glycolytic enzymes, includ...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593546/ https://ncbi.nlm.nih.gov/pubmed/28915575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9760 |
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