Induction of multispecific Th-1 type immune response against HCV in mice by protein immunization using CpG and Montanide ISA 720 as adjuvants

Recent studies demonstrate that Th1-type immune responses against a broad spectrum of hepatitis C virus (HCV) gene products are crucial to the resolution of acute HCV infection. We investigated new vaccine approaches to augment the strength of HCV-specific Th1-type immune responses. ELISPOT assay re...

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Опубликовано в: :Vaccine
Главные авторы: Qiu, Qi, Wang, Richard Yuan-Hu, Jiao, Xuanmao, Jin, Bo, Sugauchi, Fuminaka, Grandinetti, Teresa, Alter, Harvey J., Shih, J. Wai-Kuo
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593311/
https://ncbi.nlm.nih.gov/pubmed/18675871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.034
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