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MGMT methylation correlates with melphalan pelvic perfusion survival in stage III melanoma patients: a pilot study

Approximately 25% of melanoma patients with locoregional metastases are nonresponsive to new molecular target therapy and immunotherapy. When metastases are located in the pelvis, melphalan hypoxic perfusion can be an optional treatment. Because methylation of MGMT promoter increases the efficacy of...

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Bibliographische Detailangaben
Veröffentlicht in:Melanoma Res
Hauptverfasser: Guadagni, Stefano, Fiorentini, Giammaria, Clementi, Marco, Palumbo, Giancarlo, Masedu, Francesco, Deraco, Marcello, De Manzoni, Giovanni, Chiominto, Alessandro, Valenti, Marco, Pellegrini, Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592983/
https://ncbi.nlm.nih.gov/pubmed/28486243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000367
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