Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9

Osteosarcoma (OS) is a malignant tumor of the bone derived from primitive transformed cells of the mesenchymal origin. Local low-linear energy transfer (LET) radiotherapy has limited benefits on OS owing to its radioresistance. Thus, this study aimed to investigate the effects of high-LET radiation...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Kim, Eun Ho, Kim, Mi-Sook, Lee, Kyung-Hee, Sai, Sei, Jeong, Youn Kyoung, Koh, Jae-Soo, Kong, Chang-Bae
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592849/
https://ncbi.nlm.nih.gov/pubmed/28849129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4102
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