Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

Breast cancer cells disseminate through TIE2/MENA(Calc)/MENA(INV)-dependent cancer cell intravasation sites, called tumor microenvironment of metastasis (TMEM), which are clinically validated as prognostic markers of metastasis in breast cancer patients. Using fixed tissue and intravital imaging of...

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Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Karagiannis, George S., Pastoriza, Jessica M., Wang, Yarong, Harney, Allison S., Entenberg, David, Pignatelli, Jeanine, Sharma, Ved P., Xue, Emily A., Cheng, Esther, D’Alfonso, Timothy M., Jones, Joan G., Anampa, Jesus, Rohan, Thomas E., Sparano, Joseph A., Condeelis, John S., Oktay, Maja H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592784/
https://ncbi.nlm.nih.gov/pubmed/28679654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan0026
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