Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

Breast cancer cells disseminate through TIE2/MENA(Calc)/MENA(INV)-dependent cancer cell intravasation sites, called tumor microenvironment of metastasis (TMEM), which are clinically validated as prognostic markers of metastasis in breast cancer patients. Using fixed tissue and intravital imaging of...

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Publicado en:Sci Transl Med
Main Authors: Karagiannis, George S., Pastoriza, Jessica M., Wang, Yarong, Harney, Allison S., Entenberg, David, Pignatelli, Jeanine, Sharma, Ved P., Xue, Emily A., Cheng, Esther, D’Alfonso, Timothy M., Jones, Joan G., Anampa, Jesus, Rohan, Thomas E., Sparano, Joseph A., Condeelis, John S., Oktay, Maja H.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592784/
https://ncbi.nlm.nih.gov/pubmed/28679654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan0026
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