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Structural Characterization of Histatin 5–Spermidine Conjugates: A Combined Experimental and Theoretical Study
Histatin 5 (Hst5) is a naturally occurring antimicrobial peptide that acts as the first line of defense against oral candidiasis. It has been shown that conjugation of the active Hst5 fragment, Hst5(4–15), and the polyamine spermidine (Spd) improves the candidacidal effect. Knowledge about the struc...
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| Publicado en: | J Chem Inf Model |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5592739/ https://ncbi.nlm.nih.gov/pubmed/28586222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00150 |
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