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Structural Characterization of Histatin 5–Spermidine Conjugates: A Combined Experimental and Theoretical Study

Histatin 5 (Hst5) is a naturally occurring antimicrobial peptide that acts as the first line of defense against oral candidiasis. It has been shown that conjugation of the active Hst5 fragment, Hst5(4–15), and the polyamine spermidine (Spd) improves the candidacidal effect. Knowledge about the struc...

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Bibliographic Details
Published in:J Chem Inf Model
Main Authors: Jephthah, Stephanie, Henriques, João, Cragnell, Carolina, Puri, Sumant, Edgerton, Mira, Skepö, Marie
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592739/
https://ncbi.nlm.nih.gov/pubmed/28586222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00150
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