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Structural Characterization of Histatin 5–Spermidine Conjugates: A Combined Experimental and Theoretical Study

Histatin 5 (Hst5) is a naturally occurring antimicrobial peptide that acts as the first line of defense against oral candidiasis. It has been shown that conjugation of the active Hst5 fragment, Hst5(4–15), and the polyamine spermidine (Spd) improves the candidacidal effect. Knowledge about the struc...

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Jephthah, Stephanie, Henriques, João, Cragnell, Carolina, Puri, Sumant, Edgerton, Mira, Skepö, Marie
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592739/
https://ncbi.nlm.nih.gov/pubmed/28586222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00150
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