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Phosphatidylinositol 3,5-bisphosphate is involved in methylglyoxal-induced activation of the Mpk1 mitogen-activated protein kinase cascade in Saccharomyces cerevisiae

Methylglyoxal (MG) is a natural metabolite derived from glycolysis, and this 2-oxoaldehyde has been implicated in some diseases including diabetes. However, the physiological significance of MG for cellular functions is yet to be fully elucidated. We previously reported that MG activates the Mpk1 (M...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nomura, Wataru, Maeta, Kazuhiro, Inoue, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592679/
https://ncbi.nlm.nih.gov/pubmed/28743744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791590
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