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Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator–activated receptor γ (PPARγ) during adipocyte differentiation

The breakdown of stored fat deposits into its components is a highly regulated process that maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated transcription of Atgl, the enzyme that mediates the rate-limiting step in lipolysis, is a key point of this regulation....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roy, Debasish, Farabaugh, Kenneth T., Wu, Jing, Charrier, Alyssa, Smas, Cynthia, Hatzoglou, Maria, Thirumurugan, Kavitha, Buchner, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592664/
https://ncbi.nlm.nih.gov/pubmed/28726642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783043
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