Microtubule-assisted altered trafficking of astrocytic gap junction protein connexin 43 is associated with depletion of connexin 47 during mouse hepatitis virus infection

Gap junctions (GJs) are important for maintenance of CNS homeostasis. GJ proteins, connexin 43 (Cx43) and connexin 47 (Cx47), play a crucial role in production and maintenance of CNS myelin. Cx43 is mainly expressed by astrocytes in the CNS and forms gap junction intercellular communications between...

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Udgivet i:J Biol Chem
Main Authors: Basu, Rahul, Bose, Abhishek, Thomas, Deepthi, Das Sarma, Jayasri
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592656/
https://ncbi.nlm.nih.gov/pubmed/28566289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786491
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