Targeted Delivery of Neutralizing Anti-C5 Antibody to Renal Endothelium Prevents Complement-Dependent Tissue Damage

Complement activation is largely implicated in the pathogenesis of several clinical conditions and its therapeutic neutralization has proven effective in preventing tissue and organ damage. A problem that still needs to be solved in the therapeutic control of complement-mediated diseases is how to a...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Durigutto, Paolo, Sblattero, Daniele, Biffi, Stefania, De Maso, Luca, Garrovo, Chiara, Baj, Gabriele, Colombo, Federico, Fischetti, Fabio, Di Naro, Antonio F., Tedesco, Francesco, Macor, Paolo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592221/
https://ncbi.nlm.nih.gov/pubmed/28932227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01093
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