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Population Pharmacokinetics of Cladribine in Patients with Multiple Sclerosis
PURPOSE: The aims of this study were to characterize the concentration–time course of cladribine (CdA) and its main metabolite 2-chloroadenine (CAde), estimate interindividual variability in pharmacokinetics (PK), and identify covariates explaining variability in the PK of CdA. METHODS: This populat...
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| Publicado no: | Clin Pharmacokinet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591805/ https://ncbi.nlm.nih.gov/pubmed/28255849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0516-6 |
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