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Genetic Code Optimization for Cotranslational Protein Folding: Codon Directional Asymmetry Correlates with Antiparallel Betasheets, tRNA Synthetase Classes

A new codon property, codon directional asymmetry in nucleotide content (CDA), reveals a biologically meaningful genetic code dimension: palindromic codons (first and last nucleotides identical, codon structure XZX) are symmetric (CDA = 0), codons with structures ZXX/XXZ are 5′/3′ asymmetric (CDA = ...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Seligmann, Hervé, Warthi, Ganesh
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591391/
https://ncbi.nlm.nih.gov/pubmed/28924459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2017.08.001
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