CXCL12 Mediates Aberrant Costimulation of B Lymphocytes in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Immunodeficiency

The Warts, Hypogammaglobulinemia, Infections, Myelokathexis (WHIM) syndrome is an immunodeficiency caused by mutations in chemokine receptor CXCR4. WHIM patient adaptive immunity defects remain largely unexplained. We have previously shown that WHIM-mutant T cells form unstable immunological synapse...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Roselli, Giuliana, Martini, Elisa, Lougaris, Vassilios, Badolato, Raffaele, Viola, Antonella, Kallikourdis, Marinos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591327/
https://ncbi.nlm.nih.gov/pubmed/28928741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01068
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