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Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy

The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown. Herein, we studied bioactive lipid mediator (LM) profiles of tendon-derived stromal cells isolated from healthy donors and patients with chronic tendinopathy. Interleukin(IL)-1β t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dakin, Stephanie G., Ly, Lucy, Colas, Romain A., Oppermann, Udo, Wheway, Kim, Watkins, Bridget, Dalli, Jesmond, Carr, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591234/
https://ncbi.nlm.nih.gov/pubmed/28887458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11188-y
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