Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid

The differentiation of resident tissue macrophages from embryonic precursors and that of inflammatory macrophages from bone marrow cells leads to macrophage heterogeneity. Further plasticity is displayed through their ability to be polarized as subtypes M1 and M2 in a cell culture microenvironment....

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Publicat a:Sci Rep
Autors principals: Sorgi, Carlos A., Zarini, Simona, Martin, Sarah A., Sanchez, Raphael L., Scandiuzzi, Rodrigo F., Gijón, Miguel A., Guijas, Carlos, Flamand, Nicolas, Murphy, Robert C., Faccioli, Lucia H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591212/
https://ncbi.nlm.nih.gov/pubmed/28887514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11496-3
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