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Replication protein A modulates its interface with the primed DNA template during RNA–DNA primer elongation in replicating SV40 chromosomes

The eukaryal single-stranded DNA binding protein replication protein A (RPA) binds short oligonucleotides with high affinity but exhibits low cooperativity in binding longer templates, opposite to prokaryal counterparts. This discrepancy could reflect the smaller size of the replicative template por...

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Autores principales: Mass, Gilad, Nethanel, Tamar, Lavrik, Olga I., Wold, Marc S., Kaufmann, Gabriel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55912/
https://ncbi.nlm.nih.gov/pubmed/11557822
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