Genetic polymorphisms of CYP3A4 among Chinese patients with steroid-induced osteonecrosis of the femoral head

BACKGROUND: Steroid therapy has been an important reason of nontraumatic osteonecrosis of the femoral head (ONFH). Steroids are metabolized by hepatic cytochrome P4503A, a low endogenous activity of this enzyme can contribute to the pathogenesis of ONFH. The aim of this study was to investigate the...

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Vydáno v:Medicine (Baltimore)
Hlavní autoři: Wang, Yuan, Li, Xiuling, Gao, Yaoyu, Li, Zhi, Yu, Lidong, Meng, Qingbo, Sun, Li, Wang, Jianzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591163/
https://ncbi.nlm.nih.gov/pubmed/27858915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000005332
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