Viral replication complexes are targeted by LC3-guided interferon-inducible GTPases

All viruses with positive-sense RNA genomes replicate on membranous structures in the cytoplasm, called replication complexes (RCs). RCs provide an advantageous microenvironment for viral replication, but it is unknown how the host immune system counteracts these structures. Here we show that interf...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Biering, Scott B., Choi, Jayoung, Halstrom, Rachel A., Brown, Hailey M., Beatty, Wandy L., Lee, Sanghyun, McCune, Broc T., Dominici, Erin, Williams, Lelia E., Orchard, Robert C., Wilen, Craig B., Yamamoto, Masahiro, Coers, Jörn, Taylor, Gregory A., Hwang, Seungmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591033/
https://ncbi.nlm.nih.gov/pubmed/28669671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.06.005
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