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The cardiac calsequestrin gene transcription is modulated at the promoter by NFAT and MEF-2 transcription factors

Calsequestrin-2 (CASQ2) is the main Ca(2+)-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-2 and SRF binding sites within the human CASQ2 gene (hCASQ2) promoter region are functional in neonatal cardiomyocytes. In this work, we investigated i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Estrada-Avilés, Rafael, Rodríguez, Gabriela, Zarain-Herzberg, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590987/
https://ncbi.nlm.nih.gov/pubmed/28886186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184724
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