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Maternal treatment with short-chain fatty acids modulates the intestinal microbiota and immunity and ameliorates type 1 diabetes in the offspring

We recently hypothesized that the intestinal microbiota and the innate immune system play key roles in the mechanism of Kilham Rat Virus-induced type 1 diabetes in the LEW1.WR1 rat. We used this animal model to test the hypothesis that maternal therapy with short-chain fatty acids can modulate the i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Needell, James C., Ir, Diana, Robertson, Charles E., Kroehl, Miranda E., Frank, Daniel N., Zipris, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590848/
https://ncbi.nlm.nih.gov/pubmed/28886045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183786
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