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Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space

This review describes the basic concepts and protocol to perform the real-time iontophoresis (RTI) method, the gold-standard to explore and quantify the extracellular space (ECS) of the living brain. The ECS surrounds all brain cells and contains both interstitial fluid and extracellular matrix. The...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Odackal, John, Colbourn, Robert, Odackal, Namrita Jain, Tao, Lian, Nicholson, Charles, Hrabetova, Sabina
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590668/
https://ncbi.nlm.nih.gov/pubmed/28784968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55755
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