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miR-22 suppresses tumorigenesis and improves radiosensitivity of breast cancer cells by targeting Sirt1

BACKGROUND: miR-22 has been shown to be frequently downregulated and act as a tumor suppressor in multiple cancers including breast cancers. However, the role of miR-22 in regulating the radioresistance of breast cancer cells, as well as its underlying mechanism is still not well understood. METHODS...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biol Res
Auteurs principaux: Zhang, Xia, Li, Yuehua, Wang, Dan, Wei, Xiaoer
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590131/
https://ncbi.nlm.nih.gov/pubmed/28882183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-017-0133-8
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