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Prospective replication study implicates the catechol-O-methyltransferase Val(158)Met polymorphism as a biomarker for the response to morphine in patients with cancer
Genetic differences in humans cause clinical difficulties in opioid treatment. Previous studies indicate that a single nucleotide polymorphism in the catechol-O-methyltransferase (COMT) gene (rs4680; p.Val(158)Met) may present as a predictive biomarker for the response to morphine treatment. In our...
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| Опубликовано в: : | Biomed Rep |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5590034/ https://ncbi.nlm.nih.gov/pubmed/28928973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.963 |
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