Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A

BACKGROUND: Hypoxia is negatively associated with glioblastoma (GBM) patient survival and contributes to tumour resistance. Anti-angiogenic therapy in GBM further increases hypoxia and activates survival pathways. The aim of this study was to determine the role of hypoxia-induced autophagy in GBM. M...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Autores principales: Abdul Rahim, Siti Aminah, Dirkse, Anne, Oudin, Anais, Schuster, Anne, Bohler, Jill, Barthelemy, Vanessa, Muller, Arnaud, Vallar, Laurent, Janji, Bassam, Golebiewska, Anna, Niclou, Simone P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590001/
https://ncbi.nlm.nih.gov/pubmed/28797031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.263
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