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Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed

Mycobacterium tuberculosis, the cause of Tuberculosis (TB), infects one third of the world’s population and causes substantial mortality worldwide. In its shortest format, treatment of TB requires six months of multidrug therapy with a mixture of broad spectrum and mycobacterial specific antibiotics...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wipperman, Matthew F., Fitzgerald, Daniel W., Juste, Marc Antoine Jean, Taur, Ying, Namasivayam, Sivaranjani, Sher, Alan, Bean, James M., Bucci, Vanni, Glickman, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589918/
https://ncbi.nlm.nih.gov/pubmed/28883399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10346-6
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