Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients

Hundreds of genetic loci participate to schizophrenia liability. It is also known that impaired cerebral connectivity is directly related to the cognitive and affective disturbances in schizophrenia. How genetic susceptibility and brain neural networks interact to specify a pathological phenotype in...

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Veröffentlicht in:NPJ Schizophr
Hauptverfasser: Ibrahim, El Chérif, Guillemot, Vincent, Comte, Magali, Tenenhaus, Arthur, Zendjidjian, Xavier Yves, Cancel, Aida, Belzeaux, Raoul, Sauvanaud, Florence, Blin, Olivier, Frouin, Vincent, Fakra, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589880/
https://ncbi.nlm.nih.gov/pubmed/28883405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41537-017-0027-3
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