Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in locomotor and respiratory muscles during experimental sepsis in mice

Sepsis induced loss of muscle mass and function contributes to promote physical inactivity and disability in patients. In this experimental study, mice were sacrificed 1, 4, or 7 days after cecal ligation and puncture (CLP) or sham surgery. When compared with diaphragm, locomotor muscles were more p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Morel, Jérome, Palao, Jean-Charles, Castells, Josiane, Desgeorges, Marine, Busso, Thierry, Molliex, Serge, Jahnke, Vanessa, Del Carmine, Peggy, Gondin, Julien, Arnould, David, Durieux, Anne Cécile, Freyssenet, Damien
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589872/
https://ncbi.nlm.nih.gov/pubmed/28883493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11440-5
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