Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Nonalcoholic fatty liver disease is one of the most prevalent metabolic disorders and it tightly associates with obesity, type 2 diabetes, and cardiovascular disease. Reduced mitochondrial lipid oxidation contributes to hepatic fatty acid accumulation. Here, we show that the Fas cell surface death r...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Item, Flurin, Wueest, Stephan, Lemos, Vera, Stein, Sokrates, Lucchini, Fabrizio C., Denzler, Rémy, Fisser, Muriel C., Challa, Tenagne D., Pirinen, Eija, Kim, Youngsoo, Hemmi, Silvio, Gulbins, Erich, Gross, Atan, O’Reilly, Lorraine A., Stoffel, Markus, Auwerx, Johan, Konrad, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589858/
https://ncbi.nlm.nih.gov/pubmed/28883393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00566-9
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