Cytoglobin Promotes Cardiac Progenitor Cell Survival against Oxidative Stress via the Upregulation of the NFκB/iNOS Signal Pathway and Nitric Oxide Production

Human cardiac stem/progenitor cells (hCPCs) may serve in regenerative medicine to repair the infarcted heart. However, this approach is severely limited by the poor survival of donor cells. Recent studies suggest that the mammalian globin cytoglobin (CYGB) regulates nitric oxide (NO) metabolism and...

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Publicado no:Sci Rep
Main Authors: Zhang, Shuning, Li, Xiuchun, Jourd’heuil, Frances L., Qu, Shunlin, Devejian, Neil, Bennett, Edward, Jourd’heuil, David, Cai, Chuanxi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589853/
https://ncbi.nlm.nih.gov/pubmed/28883470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11342-6
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