The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma

The pancreatic adenocarcinoma (PDAC) microenvironment is largely comprised of fibrotic tumor associated stroma (TAS) that contributes to the lethal biology of PDAC. microRNA (miRNA) are small non-coding RNAs that regulate gene expression. We hypothesized that interactions between PDAC cells and TAS...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Han, Song, Gonzalo, David H., Feely, Michael, Delitto, Daniel, Behrns, Kevin E., Beveridge, Mark, Zhang, DongYu, Thomas, Ryan, Trevino, Jose G., Schmittgen, Thomas D., Hughes, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589562/
https://ncbi.nlm.nih.gov/pubmed/28903323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10722
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