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NCCTG N0543 (Alliance): A Phase II Trial of Pharmacogenetic-Based Dosing of Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy for Advanced Small Bowel Adenocarcinoma

BACKGROUND: Oxaliplatin in combination with either 5-fluorouracil or capecitabine is commonly used as first line therapy for small bowel adenocarcinoma. The addition of irinotecan improves survival in other gastrointestinal tumors but at the cost of hematologic toxicity. We performed a phase II, coo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer
मुख्य लेखकों: McWilliams, Robert R., Foster, Nathan R., Mahoney, Michelle R., Smyrk, Thomas C., Murray, Joseph A., Ames, Matthew M., Horvath, Elise, Schneider, Daniel, Hobday, Timothy J., Jatoi, Aminah, Meyers, Jeffrey P., Goetz, Matthew P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589489/
https://ncbi.nlm.nih.gov/pubmed/28493308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30766
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