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Microfluidic Platform for Efficient Nanodisc Assembly, Membrane Protein Incorporation, and Purification

The characterization of integral membrane proteins presents numerous analytical challenges on account of their poor activity under non-native conditions, limited solubility in aqueous solutions, and low expression in most cell culture systems. Nanodiscs are synthetic model membrane constructs that o...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Wade, James H., Jones, Joshua D., Lenov, Ivan L., Riordan, Colleen M., Sligar, Stephen G., Bailey, Ryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589448/
https://ncbi.nlm.nih.gov/pubmed/28767110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7lc00601b
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