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Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes

Neurotransmitter release depends on the SNARE complex formed by syntaxin-1, synaptobrevin and SNAP-25, as well as on complexins, which bind to the SNARE complex and play active and inhibitory roles. A crystal structure of a Complexin-I fragment bearing a so-called 'superclamp' mutation bou...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Prinslow, Eric A, Brautigam, Chad A, Rizo, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589412/
https://ncbi.nlm.nih.gov/pubmed/28880148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30286
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